The analgesic properties of antidepressants have been suggested ... implicated in the pathophysiology of chronic pain, but likely also other endogenous substrates. The association between COMT ...

Among the drugs studied - which included Prozac and a cheap antidepressant called amitriptyline - only one, called duloxetine, showed any evidence for pain relief. None of the trials gathered long ...

Its draft guidance recommends antidepressants ... pain do not want to take medication long-term, and GPs do not want this either, but sometimes medication has been the only thing that brings relief.

which helps regulate mood in conditions like depression and anxiety. The drug also modifies how pain signals are processed in the central nervous system, and is also often prescribed to treat ...

Tricylic antidepressants, traditional anticonvulsants and opioids were found to be better for short-term pain relief than were newer generation anticonvulsants, a selective serotonin reuptake ...

It is taken orally, most commonly as an antidepressant, often in an extended-release tablet form. Duloxetine is also used to treat some forms of pain and works by increasing neurotransmitters in ...

The drug is used to treat depression in adults and generalized anxiety disorder in adults and children over the age of 7, according to the website. It is also used to treat pain caused by ...

Antidepressants are widely administered to chronic pain patients, but there is large interindividual variability in their efficacy and adverse effect rates that may be attributed to genetic factors.