This benefit of mipomersen is based on a novel mechanism of action that can work independently of, or synergistically with, standard medications that reduce LDL–cholesterol levels.
Current AHA guidelines call for healthy Americans to bring LDL below 100 milligrams per deciliter (mg/dL) of blood, while those who’ve had a heart attack or stroke are encouraged to drop LDL at least ...
RA: With average healthy adults LDL usually at over 100, what are the health implications of a treatment that could lower it to below 25? JE: Lowering LDL-C levels to specific and individualized ...
For adults, we know that statins can help lower LDL cholesterol roughly 18 to 60 ... through a collaboration between Consumer Reports Best Buy Drugs and the American Society of Health-System ...
[27] If patients do not reach LDL goals with diet and exercise, statins are the preferred drug therapy. For PAD patients with low HDL and high triglycerides, treatment with niacin or fibrates ...
[48] Several lipid-lowering studies have demonstrated that a large proportion of patients who achieve their LDL-C or non-HDL-C goals remain above the treatment target for apoB, which represents an ...
Results also found that the treatment ... once-a-day, low-dose tablet, to be clinically differentiated from other lipid-lowering therapies by lowering Lp(a) and small LDL-particles as well ...