Hi-C技术源于染色体构象捕获(Chromosome Conformation Capture—3C)技术,以整个细胞核为研究对象,利用高通量测序技术,结合生物信息学方法,研究全基因组范围内整个染色质DNA在空间位置上的关系,揭示染色体的三维结构。2015年,美国国立卫生研究院(NIH ...
2009). Hi-C is a 3C derivative, based on proximity ligation of cross-linked DNA with a biotin linker, which is used to pull down the fragments, followed by high-throughput sequencing. From eight ...
近几年,染色体三维结构作为崭新的研究方向,在疾病研究中的地位越来越重要,高分文章层出不穷。本月18号,来自英国Babraham研究所的科学家利用捕获Hi-C技术,发现了成千上万与特定疾病相关的新基因,包括类风湿性关节炎、1型糖尿病和Crohn氏病。小编先带 ...
One of the latest trends on Chinese social media platform Xiaohongshu is for women to share complaints about pushy government inquiries on whether they are pregnant or plan to be soon. The Chinese ...
There are many different types of cherry, including maraschino, griotte and Morello cherries, from which kirsch and Black Forest gâteaux are made. Look out for telltale punnets of deep red ...
中俄元首外交为深化两国全方位合作起到了引领定航的作用,也为壮大全球南方力量,共同推动全球治理体系改革提供了新 ...
WH editors talked to a gastroenterologist and registered dietitians to see if prebiotic sodas like Olipop and Poppi actually ...
Cherry tomatoes are available year round but are at their best from June to October. Look for firm-fleshed, well-coloured fruit with clear skin and no signs of bruising. Remove from any plastic ...
Which type of cherry tree do I have? There are three groups of cherries, based on different species, and it is important to know which you have, as established trees are pruned differently. Sweet ...
The following listing includes Camden County's candidates in countywide and municipal races on the ballot for Election Day, ...