Those on the extreme end of the depression spectrum face symptoms that impact their daily activities too and not just their ...

Studies show that antidepressants don’t always work. One psychologist explains how to take control of negative thoughts ...

Neuroscience company Neumora Therapeutics (NMRA) announced today that its experimental treatment for depression, Navacaprant, ...

Participants in clinic trial went from being unable to get out of bed to being productive and interacting with loved ones ...

In zebrafish, ketamine causes changes a brain circuit involved in "giving up." That may help explain how the drug helps ...

comzeal – stock.adobe.com “The theme for [nearly] all these medications [is] they typically ... are primarily used to treat severe depression but may also be prescribed off-label for chronic ...

Vagus nerve stimulation therapy improved the symptoms of treatment-resistant depression for nearly 500 participants in a ...

As with any medication, antidepressants may cause ... However, they may be more effective for people with severe depression than other antidepressants. Some examples of NaSSAs include mirtazapine ...

A previous, smaller study of the drug found statistically significant and clinically meaningful improvements in symptoms of depression in patients with moderate-to-severe depression. At the time ...

The trial involved nearly 500 people at 84 sites across the US who all suffered from severe depression that could not be treated effectively with medication or other approaches. Around 75 per cent ...

The decades-old anesthetic ketamine could be a game changer for treating severe depression, but there are still many questions about how the drug works, including exactly how it affects the brain ...