A new review from the Cochrane Database of Systematic Reviews confirms that antidepressants can effectively reduce symptoms of generalized anxiety disorder (GAD) in clinical trials. However, there is ...

CIII allows people who have tried at least two oral antidepressants to use the spray on its own – without the need for more ...

Existing drugs for manic depression - such as loxapine, promazine and haloperidol - can cause weight gain and a feeling of tiredness and lethargy. They have also been inconsistent at preventing ...

Johnson & Johnson has announced the FDA’s approval of a first-of-its-kind, esketamine nasal spray called Spravato for the ...

People with treatment-resistant depression can now take Spravato's ketamine-derived nasal spray as a standalone treatment.

A ketamine-based nasal spray is officially the first and only standalone therapy available for treatment-resistant depression ...

Glyph drugs are designed to be absorbed through the lymphatic system, avoiding the liver, much like dietary fats. There has been a lot of interest in using allopregnanolone to treat depression ...

Some antidepressant drugs carry a "black box warning" about ... of withdrawal from antidepressant medication as returning depression symptoms, and put clients back on medication—and, in some ...

Respondents who said they used other drugs recreationally were also likelier to say they used ketamine during the past year ...

The findings offer new insight into depression's impact on the brain and present possible new targets for treatment, experts say. The research team highlight the existing drugs pregabalin and ...