Tricyclic antidepressants (TCAs ... In addition, TCAs have analgesic effects. They reduce nerve pain by increasing ...

Because tricyclic antidepressants and SNRIs are now an integral part in the management of chronic and neuropathic pain, this paper discusses the potential role of these polymorphisms in the ...

Tricyclic antidepressants, like Norpramin and Vivactil, are primarily used to treat severe depression but may also be prescribed off-label for chronic pain, insomnia and obsessive-compulsive disorder.

Several genes are involved in the interindividual variability of the antidepressant response ... implicated in the pathophysiology of chronic pain, but likely also other endogenous substrates.

Dr Laurence Wainwright, a researcher at the University of Oxford's psychiatry department, told the BBC there is "evidence to suggest a link between tricyclic antidepressants, antipsychotics and ...