A 40-year-old man presented to the emergency department with a 5-day history of fevers, sore throat, fatigue, subjective ...

Whether extended lymphadenectomy is associated with improved disease-free and overall survival, as compared with standard lymphadenectomy, among patients with localized muscle-invasive bladder ...

U.S. states, which are better positioned than the federal government to precisely and comprehensively address the drivers of low-value health care spending, should lead the way in establishing ...

CAR T-cell manufacturing involves T-cell apheresis, CAR transduction, and expansion of transduced autologous or allogeneic T cells. To date, approved CAR T-cell products rely on lentiviral ...

In order to ensure timely testing of drugs that have been granted accelerated approval, the FDA can impose civil monetary penalties on dilatory manufacturers — but has never done so. This ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

Outcomes of elections for the presidency and Congress and in the states could have profound effects on the coverage available to tens of millions of Americans. From New York University, New York ...

The next U.S. president will inherit multiple epidemics with inequitably distributed effects. Kamala Harris and Donald Trump are likely to take divergent policy approaches to addressing these crises.

While reproductive health has drawn the spotlight in the U.S. elections, less attention has been paid to other health policy issues, in part because of the success of the Affordable Care Act.

A new report from the National Academy of Medicine discusses the challenges facing U.S. biomedical research and proposes major policy changes to strengthen and reinvigorate the biomedical research ...

When AI tools recommend confirmatory diagnostic testing, patients may face new financial burdens if these recommendations are followed by their clinicians but not yet reflected in insurance policies.