New research solves the mystery of how two different types B cells work in tandem to fight off re-infections, with ...

Although two randomised, placebo-controlled clinical trials of the type I anti-CD20 antibodies rituximab and ocrelizumab in patients with lupus nephritis failed to show a difference vs placebo in the ...

Recall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B ...

The antibody response to infection and vaccination is ... Shen and colleagues identify and characterize two distinct types of myeloid–B cell interaction that may signal solid tumour-induced ...

For patients with relapsed/refractory large B-cell lymphoma (LBCL), the autologous, CD19-directed, 4-1BB chimeric antigen ...

We aimed to explore SARS-CoV-2–specific B-cell responses, circulating antibody levels, and T-cell responses before and after the third-dose vaccine and determine which element of the immune response ...

B cell lymphoma 6 (BCL6) is an essential transcriptional factor for the humoral immune response. However, genomic deregulation of BCL6 contributes to the development of different types of lymphoma ...

By comparison, a 98% overall response rate and an 83% stringent complete ... and no prior exposure to B-cell maturation antigen (BCMA)-targeted therapy. In the current study, patients receiving ...

In the largest prospective study to date examining the use of chimeric antigen receptor (CAR)-T therapy in a community ...