It is estimated that about 50% of atherosclerotic cardiovascular disease is not driven by LDL-cholesterol – the target of most lipid-lowering drugs, including statins and PCSK9 inhibitors like ...
Our concepts of the pathogenesis of acute coronary syndromes have evolved considerably over time. Our concepts about the acute coronary syndromes have evolved markedly since the founding of the ...
Obicetrapib was tested as a monotherapy and in combination with lipid-lowering medications like statins. The topline results from the pivotal BROOKLYN trial were announced in July 2024.