Plasma concentrations of oral metronidazole are proportional to the administered dose. Oral 250mg, 500mg, or 2000mg achieved peak plasma concentrations of 6 mcg/mL, 12 mcg/mL, and 40 mcg/mL ...
Following a single intravenous dose of metronidazole 500 mg, 4 healthy subjects who underwent gastrointestinal endoscopy had peak gastric juice metronidazole concentrations of 5–6 mcg/mL at one ...
or pulse (e.g., a dose of 125 mg every 3 days for 3 weeks) strategy. If oral therapy is impossible: Metronidazole 500 mg t.i.d. intravenously for 10–14 days plus retention enema of vancomycin ...