A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life.

Each kidney contains over one million microscopic filtering units called nephrons. Each nephron is made of a tubule and is responsible for 'cleaning' the blood by removing urea and excess water ...

Research from USC Stem Cell shows the critical role of Wnt signaling in nephron progenitor cells (NPCs) during kidney development. The studies highlight how varying Wnt levels influence NPC ...

In a retrospective study, investigators compared the risk of progression to end-stage kidney disease (ESKD) following partial nephrectomy and radical nephrectomy among patients with preoperative stage ...

Nephron-sparing surgery may not reduce the risk for later kidney failure in patients with kidney cancer and stage 4 CKD. Despite the promise of nephron-sparing, new study findings suggest that the ...

Kidney stones, also called urinary stones, are rock-like substances in one or both of your kidneys. They form when you have an imbalance of minerals, like calcium or uric acid, in your urine (pee).

It also focuses on the macula densa (MD) cells, located at the vascular pole of each nephron. Nephrons are the structural ...

Rege Nephro Co., Ltd. is a clinical-stage biotech company utilizing induced pluripotent stem cell (iPSC)-based technology from the Center for iPS Cell Research and Application (CiRA), Kyoto University ...

A nephrologist is a doctor who specializes in diagnosing and treating kidney conditions. Some conditions, such as diabetes, obesity, heart disease, and high blood pressure, can raise your chance ...