A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life.

Research from USC Stem Cell shows the critical role of Wnt signaling in nephron progenitor cells (NPCs) during kidney ...

In a retrospective study, investigators compared the risk of progression to end-stage kidney disease (ESKD) following partial nephrectomy and radical nephrectomy among patients with preoperative stage ...

Nephron-sparing surgery may not reduce the risk for later kidney failure in patients with kidney cancer and stage 4 CKD. Despite the promise of nephron-sparing, new study findings suggest that the ...

Most cancers are named after the part of the body where the cancer first begins, and kidney cancer is no exception. Kidney cancer begins in the kidneys—two large, bean-shaped organs—one located to the ...

Kidney pain, also known as renal pain, can be caused by injury, disease, or infection of the kidneys. The kidneys are a pair of bean-shaped organs situated on either side of the spine that are ...

Low nephron mass is associated with intrauterine malnutrition, low birthweight, preterm birth and congenital renal hypoplasia/dysplasia. The second hit is the development of overweight or obesity ...