HMG-CoA reductase inhibitors, better known as statins, are medications taken to lower cholesterol levels. Examples of statins include Lipitor (atorvastatin), lovastatin, and Zocor (simvastatin).
AstraZeneca has bought rights to an orally-active drug that inhibits PCSK9, offering a patient-friendly alternative to current cholesterol-lowering therapies that have to be delivered via a needle.
Cutting-edge fluorescent cholesterol probes now enable scientists to visualize cholesterol movement and distribution in live cells with unprecedented detail. By combining computer simulations with ...
Verve Therapeutics has started dosing patients in a phase 1b trial of its in vivo gene-editing drug for high cholesterol, designed to permanently switch off the PCSK9 gene with a one-shot treatment.