自2019年Nature首次报道乳酸化修饰，乳酸这个“代谢废物”一跃成为“宝藏小分子”，可谓“十年窗下无人问，一举成名天下知”。殊不知，作为三羧酸循环（TCA）中间产物的衣康酸（Itaconate，ITA）跟乳酸竟有相同的境遇，从一开始的“另作他用”，到如今发现其重要的生物学功能，特别是在免疫调控研究领域。今天，小编带你一起了解一下衣康酸的“前世”与“今生”。 01、衣康酸的发现与发展 衣康酸的发 ...

IT is generally understood that, in the action of carboxylase on pyruvic acid or other allied keto acics, carbon dioxide is directly split off. The following experiments show that this is not so ...

In addition to extensive research on mechanisms through which the Warburg effect promotes tumor growth, the tricarboxylic acid cycle (TCA) serves as a crucial anabolic hub supporting tumor growth (51, ...

The content of tartaric acid in the finished wine not to be less than 1,500 ppm weight by volume. n/a (d) Grape juice (d) Acidity regulator (d) Good Manufacturing Practice n/a (e) Ice cream mix; Ice ...

Results: Out of 40 that were selected and studied due to their involvement in established cases of PD, seven significantly different metabolites between PD cases and healthy control subjects were ...