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Tretinoin is a medication used to treat acne and sun-damaged skin. It can’t erase deep wrinkles, but it can help improve the appearance of surface wrinkles, fine lines, and dark spots.

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Topical retinoids (for example, tretinoin) and retinoid analogues (for example, adapalene and tazarotene) help normalize hyperkeratinization and have demonstrated significant anti-inflammatory ...