This was immediately followed by a 5-1 stretch in which the Cardinals got to 6-4 and first place in the NFC West. At this ...

Preview the Week 18 matchup between the Arizona Cardinals and San Francisco 49ers with predictions, odds, over/under, spread, betting lines and more.

Despite that focus, there was also an acknowledgment of what finishing the season strongly would mean. By beating the 49ers, ...

The Arizona Cardinals concluded their NFL regular season schedule with a decisive 47-24 victory over the San Francisco 49ers Sunday at State Farm Stadium.

WR Jauan Jennings speaks out on his ejection against the Cardinals, calling it a mistake. Get the full details on his perspective.

Here are our experts' predictions for this NFC West matchup. The Cardinals are favorites to defeat the 49ers, according to the BetMGM NFL odds. Not interested in this game? Check out expert picks ...

Kyler Murray has started all 16 games for the Cardinals in his first full season back following knee surgery a couple seasons ago. The veteran has led the Cardinals through an up and down campaign ...

D.J. Reed's path to free agency started with the San Francisco 49ers, who drafted him in the fifth round of the 2018 NFL ...

With their talismanic QB out for their Week 18 clash with the Cardinals, the 49ers will sit Brock Purdy for their closer as they look ahead to next season.

The Arizona Cardinals have one final game left this season, closing it out at home against the San Francisco 49ers. Kickoff from State Farm Stadium is at 4:25 p.m. ET (2:25 p.m. Arizona time ...

The Arizona Cardinals play their season finale at home in Week 18 against the San Francisco 49ers. Kickoff from State Farm Stadium is at 4:25 p.m. ET (2:25 p.m. Arizona time). The Cardinals have ...

GLENDALE, Ariz. -- Neither the Arizona Cardinals or San Francisco 49ers will be headed to the playoffs this season, but when rivals collide, like these two will at 4:25 p.m. Eastern Sunday on FOX ...