The NFL has handed down fines to multiple San Francisco 49ers players for their actions during last weekend's game against the Miami Dolphins, per ...

San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...

The rematch of the NFC Championship Game will look nothing like last season's NFC Championship Game. The 49ers rallied from a ...

The last time Brock Purdy faced the Lions, he beat them in the NFC Championship Game. Now the Lions are coming back to town for revenge. And they're ...

The 49ers surprisingly signed veteran center Matt Hennessy off the Atlanta Falcons practice squad to a two-year deal this week. On Friday, offensive ...

Last time the 49ers faced Detroit, they won but also gave up 31 points. And that was in the NFC Championship Game last season when the 49ers were good.

Tight end George Kittle is known for being one of the most upbeat and positive personalities in the San Francisco 49ers ...

The playoff-eliminated San Francisco 49ers are set to host the Detroit Lions on Monday night in a rematch of last season's ...

Detroit's defensive injuries will probably catch up to them in the postseason, but the 49ers don't look to have enough in the ...

Videos are auto-populated by an affiliate. This site has no control over the videos that appear above. The San Francisco ...

Nick Sorensen has been heavily criticized for the underwhelming performance of the San Francisco 49ers' defense this season.

Dan Campbell and Kyle Shanahan couldn't be any different. They face each other Monday night. And technically, they're both ...