Primary and review articles published in English were identified by a MEDLINE (1966-June 2003) search using the MeSH terms "hot flashes," "hot flushes," "menopause," and "serotonin reuptake inhibitor.

and severity of hot flashes, although the reductions are not as great as those observed with estrogen therapy. These antidepressants were generally well tolerated, with the primary adverse events ...

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