Plasmacytoid dendritic cells (pDC) primarily function as weak antigen-presenting cells (APC), but have also been shown to ...

A single amino acid change in a neuronal ion channel called KCNQ2 blocks ion flow, prevents protein localization on axons, and results in severe epilepsy and slowed neurological development.

Background and objective Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic ...

Objective While emergency care for sudden cardiac arrest (SCA) is strictly regulated in professional football, the situation ...

Hypoxia contributes to cancer resistance to both standard therapies and immunotherapy. This work demonstrates that tumor ...

Written, informed consent was obtained (from the next of kin in cases of incapacity). Approval was from the Lothian Research Ethics Committee (13/SS/0157, 15-HV-013). Flow cytometry data were analysed ...

This important work substantially advances our understanding of reactive oxygen species (ROS) as a regenerative signal during postnatal cerebellum repair by activating adaptive progenitor ...

Graphs were created using graphPad prism V.5.0 and are presented as the mean±SEM unless otherwise stated. The level of statistical significance was set at 0.05 and all F and p values are reported to ...