High CDC20 expression promotes aneuploid cancer cell sensitivity to spindle assembly checkpoint (SAC) inhibition by ...

Objectives SLE is a multifaceted autoimmune disorder with a complex pathogenesis involving genetic, environmental and ...

This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...

Anavex's financial health is stable with cash runway into 2028, but rising expenses are expected. Click here to find out why ...

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

The Primary Aldosteronism Medical Treatment Outcome (PAMO) criteria represent an internationally developed outcome standard ...

Skeletal muscle atrophy is an important feature of cancer cachexia, which can be induced by chemotherapy, and affects the survival and quality of life of cancer patients seriously. No specific drugs ...

AUTS2 syndrome patients often exhibit microcephaly, yet its etiological mechanism remains unclear. This study reveals that ...

A descriptive analysis of extracted data was performed. Statistical analysis was carried out using SPSS V.18 and GraphPad software. The dose ranged from 3.1 to 93.8 mg/kg/day (oral) and 3.2 to 76.9 mg ...

Written, informed consent was obtained (from the next of kin in cases of incapacity). Approval was from the Lothian Research Ethics Committee (13/SS/0157, 15-HV-013). Flow cytometry data were analysed ...

Anavex Life Sciences' Blarcamesine trial raises concerns over approval. Learn why AVXL stock is undervalued, reflecting the ...

Ke, X. and Ma, T. (2025) Protective Effect of Liraglutide on Early Renal Fibrosis in Diabetes Mice. Journal of Biosciences and Medicines, 13, 84-91. doi: 10.4236/jbm.2025.131008 .