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生物通
39 分钟
METTL3 调控缺氧诱导心肌细胞自噬的研究解读
复旦大学附属中山医院等多单位的研究人员 Linnan Li、Hao Cheng 等人在《Cell Death Discovery》期刊上发表了题为 “METTL3 regulates autophagy of hypoxia - induced cardiomyocytes by targeting ATG7” 的论文。该研究揭示了 METTL3 ...
生物通
1 天
FLAD1拷贝数扩增通过脂质代谢促进三阴性乳腺癌的进展
拷贝数改变在三阴性乳腺癌患者中经常发生。在这里,作者确定了FAD合成酶(FLAD1)在TNBC中作用的拷贝数扩增,并从机制上证明了这种扩增通过FLAD1/LSD1/SREBP1轴增加脂质代谢来驱动肿瘤发生。
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