The twice-daily topical application of 1% metroindazole cream was compared with 250 mg ... of this time the median number of papules in the metronidazole-treated group was reduced to 8% of the ...

Topical antibiotics can also speed resolution of POD. One percent metronidazole cream is effective when applied twice daily (Veien et al., 1991). In one case series, 79% of patients responded to 2 ...