In zebrafish, ketamine causes changes a brain circuit involved in "giving up." That may help explain how the drug helps ...

Participants in clinic trial went from being unable to get out of bed to being productive and interacting with loved ones ...

Those on the extreme end of the depression spectrum face symptoms that impact their daily activities too and not just their ...

If you or a loved one is struggling with anxiety or depression, contact the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 800-662-4357 for information on ...

The company just released data from the first of those trials, which found the drug no better than a placebo at alleviating depression. The “KOASTAL-1” study had a main treatment period of six weeks ...

A previous, smaller study of the drug found statistically significant and clinically meaningful improvements in symptoms of depression in patients with moderate-to-severe depression. At the time ...

Studies show that antidepressants don’t always work. One psychologist explains how to take control of negative thoughts ...

Vagus nerve stimulation therapy improved the symptoms of treatment-resistant depression for nearly 500 participants in a major clinical trial.

500 people at 84 sites across the US who suffered from severe depression and could not treat the condition effectively through medication and other approaches were involved in the study.