Primary and review articles published in English were identified by a MEDLINE (1966-June 2003) search using the MeSH terms "hot flashes," "hot flushes," "menopause," and "serotonin reuptake inhibitor.
The studies were conducted over short periods with no efficacy information beyond 13 weeks of treatment ... observed with estrogen therapy. These antidepressants were generally well tolerated ...
despite menopause guidelines that state antidepressants shouldn’t be the first option for addressing the low mood linked with perimenopause and menopause, multiple surveys have shown that ...