Familiar with the powerful influence of the gut–brain axis, Maraganore and his team set out to investigate how the ...

Catch our top content from 2024! What were the overall winners? Which were our most impactful features and new initiatives ...

Novel peptide-modified lipid nanoparticles can cross the blood–brain barrier and target neurons, taking one step closer to ...

HIF1α identified as key regulator that induces cancer-killing ability of hypoxic T cells, playing a role in ICB resistance.

Legacy sequencing technologies have, undoubtedly, made comprehensive transcriptome analysis possible and are invaluable for ...

Microglia have been revealed to first help spread Alzheimer’s disease pathology across the brain and then activate to limit ...

Quantitative PCR (qPCR) is a widely utilized technique for the semiquantitative study of gene expression. However, its accuracy and reproducibility depend significantly on the proper use of assay ...

A light-induced gene therapy can damage cancer cells’ mitochondria, triggering widespread cancer cell death. Researchers at Ohio State University (OH, USA) have developed a light-induced gene therapy ...

Implementing digital PCR (dPCR) into your research can offer unparalleled sensitivity and absolute quantification, overcoming many of the limitations of qPCR. However, the quality of dPCR data can ...

Single-cell analysis helps uncover how the BK virus replicates, opening the door to new drug targets. BK polyomavirus (BKPyV) is a major cause of kidney transplant failure. Without a complete ...