Phagosome - Wikipedia
A phagosome is formed by the fusion of the cell membrane around a microorganism, a senescent cell or an apoptotic cell. Phagosomes have membrane-bound proteins to recruit and fuse with lysosomes to form mature phagolysosomes .
Formation and Maturation of the Phagosome: A Key Mechanism …
2020年8月25日 · Phagosome maturation is initiated after the newly formed phagosome is separated from the cell membrane. The initial step in the formation of early phagosomes is the interaction with early endosomes.
KEGG PATHWAY: Phagosome
A phagosome is formed when the specific receptors on the phagocyte surface recognize ligands on the particle surface. After formation, nascent phagosomes progressively acquire digestive characteristics.
Phagosome - an overview | ScienceDirect Topics
Phagosome - an overview | ScienceDirect Topics. Phagosome. In subject area: Neuroscience. A phagosome is a subcellular organelle that plays a crucial role in the immune system by transforming into a toxic environment to destroy pathogens through the production of …
Phagocytosis: Current Biology - Cell Press
2011年7月26日 · Phagocytosis is defined as the receptor-mediated engulfment of large (≥0.5 μm) particles into plasma membrane-derived vacuoles called phagosomes.
Formation and Maturation of the Phagosome: A Key Mechanism …
2020年8月25日 · After internalizing microbial pathogens via phagocytosis, phagosomes undergo a series of 'maturation' steps, to form an increasingly acidified compartment and subsequently fuse with the lysosome to develop into phagolysosomes and …
Phagosome maturation: going through the acid test | Nature …
Phagosome maturation is the process by which internalized particles (such as bacteria and apoptotic cells) are trafficked into a series of increasingly acidified membrane-bound structures,...
Phagosome - an overview | ScienceDirect Topics
Phagosome is a plasma membrane-bound vacuole formed after professional phagocytes (e.g., macrophages and amoebae) engulf invading pathogens or foreign particles. From: Molecular Medical Microbiology (Third Edition), 2024
The macrophage marches on its phagosome: dynamic assays of phagosome …
2009年7月10日 · The ancestral function of phagosomes is digestion; however, through evolution this degradative capacity has become pivotal to the adaptive immune response by processing antigens to be presented...
The life cycle of phagosomes: formation, maturation, and resolution
Phagocytosis, the regulated uptake of large particles (>0.5 μm in diameter), is essential for tissue homeostasis and is also an early, critical component of the innate immune response. Phagocytosis can be conceptually divided into three stages: …
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